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Co-regulated gene expression of splicing factors as drivers of cancer progression

Splicing factors (SFs) act in dynamic macromolecular complexes to modulate RNA processing. To understand the complex role of SFs in cancer progression, we performed a systemic analysis of the co-regulation of SFs using primary tumor RNA sequencing data. Co-regulated SFs were associated with aggressi...

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Publicat a:Sci Rep
Autors principals: Koedoot, Esmee, Smid, Marcel, Foekens, John A., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445126/
https://ncbi.nlm.nih.gov/pubmed/30940821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40759-4
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