Co-regulated gene expression of splicing factors as drivers of cancer progression

Splicing factors (SFs) act in dynamic macromolecular complexes to modulate RNA processing. To understand the complex role of SFs in cancer progression, we performed a systemic analysis of the co-regulation of SFs using primary tumor RNA sequencing data. Co-regulated SFs were associated with aggressi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koedoot, Esmee, Smid, Marcel, Foekens, John A., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445126/
https://ncbi.nlm.nih.gov/pubmed/30940821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40759-4
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