Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

Screening for effective candidate drugs for breast cancer has shifted from two-dimensional (2D) to three-dimensional (3D) cultures. Here we systematically compared the transcriptomes of these different culture conditions by RNAseq of 14 BC cell lines cultured in both 2D and 3D conditions. All 3D BC...

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Vydáno v:Sci Rep
Hlavní autoři: Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012355/
https://ncbi.nlm.nih.gov/pubmed/33790333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86664-7
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