Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic opportunities. Recently, splicing factors have gained attention as potential targets for cancer treatment. Here we systematically evaluated the role of RNA splicing factors in TNBC cel...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Koedoot, Esmee, van Steijn, Eline, Vermeer, Marjolein, González-Prieto, Román, Vertegaal, Alfred C. O., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919097/
https://ncbi.nlm.nih.gov/pubmed/33648524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01863-4
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