Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic opportunities. Recently, splicing factors have gained attention as potential targets for cancer treatment. Here we systematically evaluated the role of RNA splicing factors in TNBC cel...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Koedoot, Esmee, van Steijn, Eline, Vermeer, Marjolein, González-Prieto, Román, Vertegaal, Alfred C. O., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919097/
https://ncbi.nlm.nih.gov/pubmed/33648524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01863-4
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