Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

Ttriple-negative breast cancer (TNBC) is an aggressive and highly metastatic breast cancer subtype. Enhanced TNBC cell motility is a prerequisite of TNBC cell dissemination. Here, we apply an imaging-based RNAi phenotypic cell migration screen using two highly motile TNBC cell lines (Hs578T and MDA-...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Koedoot, Esmee, Fokkelman, Michiel, Rogkoti, Vasiliki-Maria, Smid, Marcel, van de Sandt, Iris, de Bont, Hans, Pont, Chantal, Klip, Janna E., Wink, Steven, Timmermans, Mieke A., Wiemer, Erik A. C., Stoilov, Peter, Foekens, John A., Le Dévédec, Sylvia E., Martens, John W. M., van de Water, Bob
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611796/
https://ncbi.nlm.nih.gov/pubmed/31278301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11020-3
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