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Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex
Kinetochore localized Mad1 is essential for generating a “wait anaphase” signal during mitosis, hereby ensuring accurate chromosome segregation. Inconsistent models for the function and quantitative contribution of the two mammalian Mad1 kinetochore receptors: Bub1 and the Rod‐Zw10‐Zwilch (RZZ) comp...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443202/ https://ncbi.nlm.nih.gov/pubmed/30782962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100977 |
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