טוען...
Coupling of Cdc20 inhibition and activation by BubR1
Tight regulation of the APC/C-Cdc20 ubiquitin ligase that targets cyclin B1 for degradation is important for mitotic fidelity. The spindle assembly checkpoint (SAC) inhibits Cdc20 through the mitotic checkpoint complex (MCC). In addition, phosphorylation of Cdc20 by cyclin B1–Cdk1 independently inhi...
שמור ב:
| הוצא לאור ב: | J Cell Biol |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Rockefeller University Press
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8025235/ https://ncbi.nlm.nih.gov/pubmed/33819340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202012081 |
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