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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Proper segregation of chromosomes depends on a functional spindle assembly checkpoint (SAC) and requires kinetochore localization of the Bub1 and Mad1/Mad2 checkpoint proteins. Several aspects of Mad1/Mad2 kinetochore recruitment in human cells are unclear and in particular the underlying direct int...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472792/ https://ncbi.nlm.nih.gov/pubmed/28604727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15822 |
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