Phospho-dependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint

The spindle assembly checkpoint (SAC) is the major surveillance system that ensures sister chromatids do not separate until all chromosomes are correctly bi-oriented during mitosis. Components of the checkpoint include Mad1, Mad2, Mad3(BubR1), Bub3 and the kinases Bub1, Mph1(Mps1) and Aurora B [1]....

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Main Authors: Shepperd, Lindsey A., Meadows, John C., Sochaj, Alicja M., Lancaster, Theresa C., Zou, Juan, Buttrick, Graham J., Rappsilber, Juri, Hardwick, Kevin G., Millar, Jonathan B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780767/
https://ncbi.nlm.nih.gov/pubmed/22521786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.03.051
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