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Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors

The spindle checkpoint is the prime cell cycle control mechanism that ensures sister chromatids are bi-oriented before anaphase takes place. Aurora B kinase, the catalytic subunit of the chromosome passenger complex, both destabilises kinetochore attachments that do not generate tension and simultan...

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Detalhes bibliográficos
Main Authors: Meadows, John C., Shepperd, Lindsey A., Vanoosthuyse, Vincent, Lancaster, Theresa C., Sochaj, Alicja M., Buttrick, Graham J., Hardwick, Kevin G., Millar, Jonathan B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792844/
https://ncbi.nlm.nih.gov/pubmed/21664573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.05.008
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