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A Novel Protein Phosphatase 1-Dependent Spindle Checkpoint Silencing Mechanism
The spindle checkpoint is a surveillance system acting in mitosis to delay anaphase onset until all chromosomes are properly attached to the mitotic spindle [1, 2]. When the checkpoint is activated, the Mad2 and Mad3 proteins directly bind and inhibit Cdc20, which is an essential activator of an E3...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cell Press
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791888/ https://ncbi.nlm.nih.gov/pubmed/19592249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.060 |
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