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Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset

The spindle checkpoint delays anaphase onset in the presence of defective kinetochore-microtubule attachments. Such delays can last for just a few minutes or several hours, but very shortly after all chromosomes achieve bi-orientation, a remarkably synchronous anaphase ensues. We are beginning to un...

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Detalhes bibliográficos
Main Authors: Hardwick, Kevin G, Shah, Jagesh V
Formato: Artigo
Idioma:Inglês
Publicado em: Faculty of 1000 Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990540/
https://ncbi.nlm.nih.gov/pubmed/21173869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-55
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