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Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

Kinetochore localized Mad1 is essential for generating a “wait anaphase” signal during mitosis, hereby ensuring accurate chromosome segregation. Inconsistent models for the function and quantitative contribution of the two mammalian Mad1 kinetochore receptors: Bub1 and the Rod‐Zw10‐Zwilch (RZZ) comp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Zhang, Gang, Kruse, Thomas, Guasch Boldú, Claudia, Garvanska, Dimitriya H, Coscia, Fabian, Mann, Matthias, Barisic, Marin, Nilsson, Jakob
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443202/
https://ncbi.nlm.nih.gov/pubmed/30782962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100977
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