Cortistatin binds to TNF-α receptors and protects against osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a common degenerative disease, and tumor necrosis factor (TNF-α) is known to play a critical role in OA. Cortistatin (CST) is a neuropeptide discovered over 20  years ago, which plays a vital role in inflammatory reactions. However, it is unknown whether CST is inv...

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Vydáno v:EBioMedicine
Hlavní autoři: Zhao, Yunpeng, Li, Yuhua, Qu, Ruize, Chen, Xiaomin, Wang, Wenhan, Qiu, Cheng, Liu, Ben, Pan, Xin, Liu, Liang, Vasilev, Krasimir, Hayball, John, Dong, Shuli, Li, Weiwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443028/
https://ncbi.nlm.nih.gov/pubmed/30826358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.02.035
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