ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis

OBJECTIVE: To examine the expression of ADAMTS-7 during the progression of osteoarthritis (OA), defining its role in the pathogenesis of OA, and elucidating the molecular events involved. METHODS: ADAMTS-7 expression in cartilage of a rat OA model was assayed using immunohistochemistry. Cartilage-sp...

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Publicat a:Ann Rheum Dis
Autors principals: Lai, Yongjie, Bai, Xiaohui, Zhao, Yunpeng, Tian, Qingyun, Liu, Ben, Lin, Edward A., Chen, Yuqing, Lee, Brendan, Appleton, C Thomas G., Beier, Frank, Yu, Xiu-Ping, Liu, Chuan-ju
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418017/
https://ncbi.nlm.nih.gov/pubmed/23928557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203561
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