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MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES

The molecular apparatus that protects us against infection can also injure us by causing autoimmune or autoinflammatory disease. It now seems that at times, defects within the sensing arm of innate immunity contribute to diseases of this type. The initiation of an immune response is often microbe de...

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Détails bibliographiques
Auteur principal: Beutler, Bruce
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713013/
https://ncbi.nlm.nih.gov/pubmed/19120489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00733.x
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