Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway

The objective of the present study was to examine the potential role of ghrelin in degeneration of nucleus pulposus (NP). Lower expression levels of ghrelin were found in human NP cells stimulated with interleukin-1β (IL-1β). Moreover, exogenous ghrelin suppressed IL-1β induced degeneration and infl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Weiwei, Wu, Xihai, Qu, Ruize, Wang, Wenhan, Chen, Xiaomin, Cheng, Lei, Liu, Yaoge, Guo, Linlin, Zhao, Yunpeng, Liu, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696149/
https://ncbi.nlm.nih.gov/pubmed/29190883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19695
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