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P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner
Hemolytic diseases are frequently linked to multiorgan failure subsequent to vascular damage. Deciphering the mechanisms leading to organ injury upon hemolytic event could bring out therapeutic approaches. Complement system activation occurs in hemolytic disorders, such as sickle cell disease, but t...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442544/ https://ncbi.nlm.nih.gov/pubmed/30850533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814797116 |
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