Complement System Part I – Molecular Mechanisms of Activation and Regulation

Por Merle, Nicolas S., Church, Sarah Elizabeth, Fremeaux-Bacchi, Veronique, Roumenina, Lubka T.
Publicado no Front Immunol (2015)

Complement System Part II: Role in Immunity

Por Merle, Nicolas S., Noe, Remi, Halbwachs-Mecarelli, Lise, Fremeaux-Bacchi, Veronique, Roumenina, Lubka T.
Publicado no Front Immunol (2015)

Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R

Por Cserhalmi, Marcell, Uzonyi, Barbara, Merle, Nicolas S., Csuka, Dorottya, Meusburger, Edgar, Lhotta, Karl, Prohászka, Zoltán, Józsi, Mihály
Publicado no Front Immunol (2017)

The AAA(+) ATPase ATAD3A Controls Mitochondrial Dynamics at the Interface of the Inner and Outer Membranes

Por Gilquin, Benoît, Taillebourg, Emmanuel, Cherradi, Nadia, Hubstenberger, Arnaud, Gay, Olivia, Merle, Nicolas, Assard, Nicole, Fauvarque, Marie-Odile, Tomohiro, Shiho, Kuge, Osamu, Baudier, Jacques
Publicado em 2010

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner

Por Merle, Nicolas S., Paule, Romain, Leon, Juliette, Daugan, Marie, Robe-Rybkine, Tania, Poillerat, Victoria, Torset, Carine, Frémeaux-Bacchi, Véronique, Dimitrov, Jordan D., Roumenina, Lubka T.
Publicado no Proc Natl Acad Sci U S A (2019)

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Termin...

Por Yatime, Laure, Merle, Nicolas S., Hansen, Annette G., Friis, Niels Anton, Østergaard, Jakob A., Bjerre, Mette, Roumenina, Lubka T., Thiel, Steffen, Kristensen, Peter, Andersen, Gregers R.
Publicado no Front Immunol (2018)

The Calcium-Dependent Interaction between S100B and the Mitochondrial AAA ATPase ATAD3A and the Role of This Complex in the Cytoplasmic Processing of ATAD3A

Por Gilquin, Benoît, Cannon, Brian R., Hubstenberger, Arnaud, Moulouel, Boualem, Falk, Elin, Merle, Nicolas, Assard, Nicole, Kieffer, Sylvie, Rousseau, Denis, Wilder, Paul T., Weber, David J., Baudier, Jacques
Publicado em 2010

Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1

Por May, Olivia, Merle, Nicolas S., Grunenwald, Anne, Gnemmi, Viviane, Leon, Juliette, Payet, Cloé, Robe-Rybkine, Tania, Paule, Romain, Delguste, Florian, Satchell, Simon C., Mathieson, Peter W., Hazzan, Marc, Boulanger, Eric, Dimitrov, Jordan D., Fremeaux-Bacchi, Veronique, Frimat, Marie, Roumenina, Lubka T.
Publicado no Front Immunol (2018)

Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis

Por Merle, Nicolas S., Grunenwald, Anne, Figueres, Marie-Lucile, Chauvet, Sophie, Daugan, Marie, Knockaert, Samantha, Robe-Rybkine, Tania, Noe, Remi, May, Olivia, Frimat, Marie, Brinkman, Nathan, Gentinetta, Thomas, Miescher, Sylvia, Houillier, Pascal, Legros, Veronique, Gonnet, Florence, Blanc-Brude, Olivier P., Rabant, Marion, Daniel, Regis, Dimitrov, Jordan D., Roumenina, Lubka T.
Publicado no Front Immunol (2018)

Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles

Por Merle, Nicolas S., Grunenwald, Anne, Rajaratnam, Helena, Gnemmi, Viviane, Frimat, Marie, Figueres, Marie-Lucile, Knockaert, Samantha, Bouzekri, Sanah, Charue, Dominique, Noe, Remi, Robe-Rybkine, Tania, Le-Hoang, Marie, Brinkman, Nathan, Gentinetta, Thomas, Edler, Monika, Petrillo, Sara, Tolosano, Emanuela, Miescher, Sylvia, Le Jeune, Sylvain, Houillier, Pascal, Chauvet, Sophie, Rabant, Marion, Dimitrov, Jordan D., Fremeaux-Bacchi, Veronique, Blanc-Brude, Olivier P., Roumenina, Lubka T.
Publicado no JCI Insight (2018)