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P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner
Hemolytic diseases are frequently linked to multiorgan failure subsequent to vascular damage. Deciphering the mechanisms leading to organ injury upon hemolytic event could bring out therapeutic approaches. Complement system activation occurs in hemolytic disorders, such as sickle cell disease, but t...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442544/ https://ncbi.nlm.nih.gov/pubmed/30850533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814797116 |
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