Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives

Humans are continuously exposed to low levels of thousands of industrial chemicals, most of which are poorly characterised in terms of their potential toxicity. The new paradigm in chemical risk assessment (CRA) aims to rely on animal-free testing, with kinetics being a key determinant of toxicity w...

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Bibliografiset tiedot
Julkaisussa:Environ Int
Päätekijät: Clerbaux, Laure-Alix, Paini, Alicia, Lumen, Annie, Osman-Ponchet, Hanan, Worth, Andrew P., Fardel, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Science 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441651/
https://ncbi.nlm.nih.gov/pubmed/30856453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2019.03.003
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