Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren’s disease -derived fibroblasts

BACKGROUND: Dupuytren’s disease (DD) is a progressive, debilitating condition of the hand that can eventually cause contractures of the affected fingers. Transforming growth factor- β1 (TGF-β1) has been reported to play a key role in DD pathology. Increased expression of TGF-β1 has shown to be the m...

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Veröffentlicht in:BMC Musculoskelet Disord
Hauptverfasser: Zhou, Chaoming, Zeldin, Yael, Baratz, Mark E., Kathju, Sandeep, Satish, Latha
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441192/
https://ncbi.nlm.nih.gov/pubmed/30927912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2486-3
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