Reversal of TGF-β(1 )stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's - derived fibroblasts

BACKGROUND: Myofibroblasts, a derived subset of fibroblasts especially important in scar formation and wound contraction, have been found at elevated levels in affected Dupuytren's tissues. Transformation of fibroblasts to myofibroblasts is characterized by expression of alpha- smooth muscle ac...

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Bibliografiska uppgifter
Huvudupphovsmän: Satish, Latha, Gallo, Phillip H, Baratz, Mark E, Johnson, Sandra, Kathju, Sandeep
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125251/
https://ncbi.nlm.nih.gov/pubmed/21612641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-113
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