Developing an animal model of Dupuytren’s disease by orthotopic transplantation of human fibroblasts into athymic rat

BACKGROUND: Dupuytren’s disease (DD) is a slow, progressive fibroproliferative disorder affecting the palms of the hands. The disease is characterized by the formation of collagen rich- cords which gradually shorten by the action of myofibroblasts resulting in finger contractures. It is a disease th...

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Bibliographic Details
Published in:BMC Musculoskelet Disord
Main Authors: Satish, Latha, Palmer, Bradley, Liu, Fang, Papatheodorou, Loukia, Rigatti, Lora, Baratz, Mark E., Kathju, Sandeep
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458343/
https://ncbi.nlm.nih.gov/pubmed/26049932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-015-0597-z
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