Anti-fibrotic action of pirfenidone in Dupuytren’s disease-derived fibroblasts

BACKGROUND: Dupuytren’s disease (DD) is a complex fibro-proliferative disorder of the hand that is often progressive and eventually can cause contractures of the affected fingers. Transforming growth factor beta (TGF-β(1)) has been implicated as a key stimulator of myofibroblast activity and fascial...

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Detaylı Bibliyografya
Yayımlandı:BMC Musculoskelet Disord
Asıl Yazarlar: Zhou, Chaoming, Liu, Fang, Gallo, Phillip H., Baratz, Mark E., Kathju, Sandeep, Satish, Latha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106805/
https://ncbi.nlm.nih.gov/pubmed/27835939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-016-1326-y
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