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Anti-fibrotic action of pirfenidone in Dupuytren’s disease-derived fibroblasts
BACKGROUND: Dupuytren’s disease (DD) is a complex fibro-proliferative disorder of the hand that is often progressive and eventually can cause contractures of the affected fingers. Transforming growth factor beta (TGF-β(1)) has been implicated as a key stimulator of myofibroblast activity and fascial...
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| Publicado en: | BMC Musculoskelet Disord |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106805/ https://ncbi.nlm.nih.gov/pubmed/27835939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-016-1326-y |
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