Association of Thyroid Function Genetic Predictors With Atrial Fibrillation: A Phenome-Wide Association Study and Inverse-Variance Weighted Average Meta-analysis

IMPORTANCE: Thyroid hormone levels are tightly regulated through feedback inhibition by thyrotropin, produced by the pituitary gland. Hyperthyroidism is overwhelmingly due to thyroid disorders and is well recognized to contribute to a wide spectrum of cardiovascular morbidity, particularly the incre...

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Detalhes bibliográficos
Publicado no:JAMA Cardiol
Main Authors: Salem, Joe-Elie, Shoemaker, M. Benjamin, Bastarache, Lisa, Shaffer, Christian M., Glazer, Andrew M., Kroncke, Brett, Wells, Quinn S., Shi, Mingjian, Straub, Peter, Jarvik, Gail P., Larson, Eric B., Velez Edwards, Digna R., Edwards, Todd L., Davis, Lea K., Hakonarson, Hakon, Weng, Chunhua, Fasel, David, Knollmann, Bjorn C., Wang, Thomas J., Denny, Joshua C., Ellinor, Patrick T., Roden, Dan M., Mosley, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439628/
https://ncbi.nlm.nih.gov/pubmed/30673079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2018.4615
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