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Phenome-Wide Association Studies as a Tool to Advance Precision Medicine

Beginning in the early 2000s, the accumulation of biospecimens linked to electronic health records (EHRs) made possible genome-phenome studies (i.e., comparative analyses of genetic variants and phenotypes) using only data collected as a by-product of typical health care. In addition to disease and...

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Bibliographic Details
Published in:Annu Rev Genomics Hum Genet
Main Authors: Denny, Joshua C., Bastarache, Lisa, Roden, Dan M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480096/
https://ncbi.nlm.nih.gov/pubmed/27147087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genom-090314-024956
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