Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis - a phenome-wide association study and inverse-variance weighted meta-analysis

OBJECTIVE: To examine the hypothesis that a genetic predisposition toward rheumatoid arthritis (RA) increases the risk for 10 cardiometabolic and autoimmune disorders previously associated with RA in epidemiological studies and to define new genetic pleiotropy. METHODS: We tested the hypothesis usin...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Kawai, Vivian K., Shi, Mingjian, Feng, Qiping, Chung, Cecilia P., Liu, Ge, Cox, Nancy J., Jarvik, Gail P., Lee, Ming T.M., Hebbring, Scott J., Harley, John B., Kaufman, Kenneth M., Namjou, Bahram, Larson, Eric, Gordon, Adam S., Roden, Dan M., Stein, C. Michael, Mosley, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572512/
https://ncbi.nlm.nih.gov/pubmed/32307929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41291
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