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In Vitro and Intracellular Activity of Imipenem Combined with Tedizolid, Rifabutin, and Avibactam against Mycobacterium abscessus

Mycobacterium abscessus infections are difficult to treat because of their resistance to many antibiotics. In vitro, tedizolid combined with imipenem displayed a moderate synergistic effect (fractional inhibitory concentration index, 0.41) but no bactericidal activity. Intracellularly, tedizolid 2 μ...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Le Run, Eva, Arthur, Michel, Mainardi, Jean-Luc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437523/
https://ncbi.nlm.nih.gov/pubmed/30745387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01915-18
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