Rifabutin Is Inactivated by Mycobacterium abscessus Arr

Mycobacterium abscessus exhibits Arr (ADP-ribosyltransferase)-dependent rifampin resistance. In apparent contrast, rifabutin (RBT) has demonstrated promising activity in M. abscessus infection models, implying that RBT might not be inactivated by Arr. RBT susceptibility testing of M. abscessus Δarr...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Schäfle, Daniel, Selchow, Petra, Borer, Barbara, Meuli, Michael, Rominski, Anna, Schulthess, Bettina, Sander, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092531/
https://ncbi.nlm.nih.gov/pubmed/33318008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02215-20
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