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Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus

Streptomycin, the first drug used for the treatment of tuberculosis, shows limited activity against the highly resistant pathogen Mycobacterium abscessus. We recently identified two aminoglycoside-acetylating genes [aac(2′) and eis2] which, however, do not affect susceptibility to streptomycin. This...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dal Molin, Michael, Gut, Myriam, Rominski, Anna, Haldimann, Klara, Becker, Katja, Sander, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740355/
https://ncbi.nlm.nih.gov/pubmed/29061744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01427-17
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