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Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus

Streptomycin, the first drug used for the treatment of tuberculosis, shows limited activity against the highly resistant pathogen Mycobacterium abscessus. We recently identified two aminoglycoside-acetylating genes [aac(2′) and eis2] which, however, do not affect susceptibility to streptomycin. This...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Dal Molin, Michael, Gut, Myriam, Rominski, Anna, Haldimann, Klara, Becker, Katja, Sander, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740355/
https://ncbi.nlm.nih.gov/pubmed/29061744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01427-17
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