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Rifabutin Is Inactivated by Mycobacterium abscessus Arr

Mycobacterium abscessus exhibits Arr (ADP-ribosyltransferase)-dependent rifampin resistance. In apparent contrast, rifabutin (RBT) has demonstrated promising activity in M. abscessus infection models, implying that RBT might not be inactivated by Arr. RBT susceptibility testing of M. abscessus Δarr...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Schäfle, Daniel, Selchow, Petra, Borer, Barbara, Meuli, Michael, Rominski, Anna, Schulthess, Bettina, Sander, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092531/
https://ncbi.nlm.nih.gov/pubmed/33318008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02215-20
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