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Inhibition of the β-Lactamase Bla(Mab) by Avibactam Improves the In Vitro and In Vivo Efficacy of Imipenem against Mycobacterium abscessus

Mycobacterium abscessus pulmonary infections are treated with a macrolide (clarithromycin or azithromycin), an aminoglycoside (amikacin), and a β-lactam (cefoxitin or imipenem). The triple combination is used without any β-lactamase inhibitor, even though M. abscessus produces the broad-spectrum β-l...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lefebvre, Anne-Laure, Le Moigne, Vincent, Bernut, Audrey, Veckerlé, Carole, Compain, Fabrice, Herrmann, Jean-Louis, Kremer, Laurent, Arthur, Michel, Mainardi, Jean-Luc
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365697/
https://ncbi.nlm.nih.gov/pubmed/28096155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02440-16
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