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In Vitro and Intracellular Activity of Imipenem Combined with Rifabutin and Avibactam against Mycobacterium abscessus

Repurposing drugs may be useful as an add-on in the treatment of Mycobacterium abscessus pulmonary infections, which are particularly difficult to cure. M. abscessus naturally produces a β-lactamase, Bla(MAb), which is inhibited by avibactam. The recommended regimens include imipenem, which is hydro...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Le Run, Eva, Arthur, Michel, Mainardi, Jean-Luc
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105861/
https://ncbi.nlm.nih.gov/pubmed/29866869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00623-18
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