ロード中...
In vivo Characterization of a Selective, Orally Available, and Brain Penetrant Small Molecule GPR139 Agonist
Recently, our group along with another demonstrated that GPR139 can be activated by L-phenylalanine (L-Phe) and L-tryptophan (L-Trp) at physiologically relevant concentrations. GPR139 is discretely expressed in brain, with highest expression in medial habenula. Not only are the endogenous ligands ca...
保存先:
| 出版年: | Front Pharmacol |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2019
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437111/ https://ncbi.nlm.nih.gov/pubmed/30949055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00273 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|