Caricamento...

Cellular response to small molecules that selectively stall protein synthesis by the ribosome

Identifying small molecules that inhibit protein synthesis by selectively stalling the ribosome constitutes a new strategy for therapeutic development. Compounds that inhibit the translation of PCSK9, a major regulator of low-density lipoprotein cholesterol, have been identified that reduce LDL chol...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Liaud, Nadège, Horlbeck, Max A., Gilbert, Luke A., Gjoni, Ketrin, Weissman, Jonathan S., Cate, Jamie H. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436758/
https://ncbi.nlm.nih.gov/pubmed/30875366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008057
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !