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Cellular response to small molecules that selectively stall protein synthesis by the ribosome
Identifying small molecules that inhibit protein synthesis by selectively stalling the ribosome constitutes a new strategy for therapeutic development. Compounds that inhibit the translation of PCSK9, a major regulator of low-density lipoprotein cholesterol, have been identified that reduce LDL chol...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6436758/ https://ncbi.nlm.nih.gov/pubmed/30875366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008057 |
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