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Phenotype of POLE-mutated endometrial cancer

BACKGROUND AND PURPOSE: Individualized therapy in endometrial cancer, the most common gynaecologic cancer in the developed world, focuses on identifying specific molecular subtypes. Mutations in the exonuclease domain of the DNA polymerase epsilon (POLE) gene define one such subtype, which causes an...

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Foilsithe in:PLoS One
Main Authors: Imboden, Sara, Nastic, Denis, Ghaderi, Mehran, Rydberg, Filippa, Rau, Tilman T., Mueller, Michael D., Epstein, Elisabeth, Carlson, Joseph W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436745/
https://ncbi.nlm.nih.gov/pubmed/30917185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214318
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