Phenotype of POLE-mutated endometrial cancer

BACKGROUND AND PURPOSE: Individualized therapy in endometrial cancer, the most common gynaecologic cancer in the developed world, focuses on identifying specific molecular subtypes. Mutations in the exonuclease domain of the DNA polymerase epsilon (POLE) gene define one such subtype, which causes an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Imboden, Sara, Nastic, Denis, Ghaderi, Mehran, Rydberg, Filippa, Rau, Tilman T., Mueller, Michael D., Epstein, Elisabeth, Carlson, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436745/
https://ncbi.nlm.nih.gov/pubmed/30917185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214318
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