Interpretation of somatic POLE mutations in endometrial carcinoma

Pathogenic somatic missense mutations within the DNA polymerase epsilon (POLE) exonuclease domain define the important subtype of ultramutated tumours (‘POLE‐ultramutated’) within the novel molecular classification of endometrial carcinoma (EC). However, clinical implementation of this classifier re...

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Bibliografische gegevens
Gepubliceerd in:J Pathol
Hoofdauteurs: León‐Castillo, Alicia, Britton, Heidi, McConechy, Melissa K, McAlpine, Jessica N, Nout, Remi, Kommoss, Stefan, Brucker, Sara Y, Carlson, Joseph W, Epstein, Elisabeth, Rau, Tilman T, Bosse, Tjalling, Church, David N, Gilks, C Blake
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Ltd 2020
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Original Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065171/
https://ncbi.nlm.nih.gov/pubmed/31829442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5372
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