CLINICAL OUTCOMES OF PATIENTS WITH POLE MUTATED ENDOMETRIOID ENDOMETRIAL CANCER

OBJECTIVES: Assess outcomes of a clinical cohort of patients with endometrioid endometrial cancer (EEC) harboring somatic POLE exonuclease domain mutations (EDMs). METHODS: Patients were consented to a protocol of tumor-normal massively parallel sequencing of 410–468 cancer related genes. EECs subje...

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Publicat a:Gynecol Oncol
Autors principals: Stasenko, Marina, Tunnage, Irina, Ashley, Charles W., Rubinstein, Maria M., Latham, Alicia J., Da Cruz Paula, Arnaud, Mueller, Jennifer J., Leitao, Mario M., Friedman, Claire F., Makker, Vicky, Soslow, Robert A., DeLair, Deborah F., Hyman, David M., Zamarin, Dimitriy, Alektiar, Kaled M., Aghajanian, Carol A., Abu-Rustum, Nadeem R., Weigelt, Britta, Cadoo, Karen A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980651/
https://ncbi.nlm.nih.gov/pubmed/31757464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.10.028
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