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CLINICAL OUTCOMES OF PATIENTS WITH POLE MUTATED ENDOMETRIOID ENDOMETRIAL CANCER

OBJECTIVES: Assess outcomes of a clinical cohort of patients with endometrioid endometrial cancer (EEC) harboring somatic POLE exonuclease domain mutations (EDMs). METHODS: Patients were consented to a protocol of tumor-normal massively parallel sequencing of 410–468 cancer related genes. EECs subje...

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Détails bibliographiques
Publié dans:Gynecol Oncol
Auteurs principaux: Stasenko, Marina, Tunnage, Irina, Ashley, Charles W., Rubinstein, Maria M., Latham, Alicia J., Da Cruz Paula, Arnaud, Mueller, Jennifer J., Leitao, Mario M., Friedman, Claire F., Makker, Vicky, Soslow, Robert A., DeLair, Deborah F., Hyman, David M., Zamarin, Dimitriy, Alektiar, Kaled M., Aghajanian, Carol A., Abu-Rustum, Nadeem R., Weigelt, Britta, Cadoo, Karen A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980651/
https://ncbi.nlm.nih.gov/pubmed/31757464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.10.028
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