Single- and multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the dual endothelin receptor antagonist aprocitentan in healthy adult and elderly subjects

Lignende værker

• Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects
  af: Dingemanse, Jasper, et al.
  Udgivet: (2002)
• Effects of the Dual Endothelin Receptor Antagonist Aprocitentan on Body Weight and Fluid Homeostasis in Healthy Subjects on a High Sodium Diet
  af: Gueneau de Mussy, Pierre, et al.
  Udgivet: (2020)
• Clinical Pharmacokinetics and Pharmacodynamics of the Endothelin Receptor Antagonist Macitentan
  af: Sidharta, P. N., et al.
  Udgivet: (2015)
• Clinical Evaluation of QTc Interval Prolongation With the Dual Endothelin Receptor Antagonist Aprocitentan
  af: P.N. Sidharta PharmD, PhD, et al.
  Udgivet: (2025-09-01)
• Investigation of mutual pharmacokinetic interactions between macitentan, a novel endothelin receptor antagonist, and sildenafil in healthy subjects
  af: Sidharta, Patricia N, et al.
  Udgivet: (2014)