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Top-Down Characterization of Proteins with Intact Disulfide Bonds Using Activated-Ion Electron Transfer Dissociation

Here we report the fragmentation of disulfide linked intact proteins using activated-ion electron transfer dissociation (AI-ETD) for top-down protein characterization. This fragmentation method is then compared to the alternative methods of HCD, ETD, and EThcD. We analyzed multiple precursor charge...

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Bibliografski detalji
Izdano u:Anal Chem
Glavni autori: Rush, Matthew J.P., Riley, Nicholas M., Westphall, Michael S., Coon, Joshua J.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434944/
https://ncbi.nlm.nih.gov/pubmed/29949341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01113
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