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Activated Ion Electron Transfer Dissociation Enables Comprehensive Top-Down Protein Fragmentation
Here we report the first demonstration of near-complete sequence coverage of intact proteins using activated ion-electron transfer dissociation (AI-ETD), a method that leverages concurrent infrared photo-activation to enhance electron-driven dissociation. AI-ETD produces mainly c/z-type product ions...
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| Pubblicato in: | J Proteome Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555583/ https://ncbi.nlm.nih.gov/pubmed/28608681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00249 |
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