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Top-Down Characterization of an Intact Monoclonal Antibody using Activated Ion-Electron Transfer Dissociation
Monoclonal antibodies (mAbs) are important therapeutic glycoproteins, but their large size and structural complexity make them difficult to rapidly characterize. Top-down mass spectrometry (MS) has potential to overcome challenges of other common approaches by minimizing sample preparation and prese...
Shranjeno v:
| izdano v: | Anal Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8210841/ https://ncbi.nlm.nih.gov/pubmed/32608969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00705 |
| Oznake: |
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