Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics

Top-down proteomics offers the potential for full protein characterization, but many challenges remain for this approach, including efficient protein separations and effective fragmentation of intact proteins. Capillary zone electrophoresis (CZE) has shown great potential for separation of intact pr...

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Veröffentlicht in:Anal Chem
Hauptverfasser: Zhao, Yimeng, Riley, Nicholas M., Sun, Liangliang, Hebert, Alexander S., Yan, Xiaojing, Westphall, Michael S., Rush, Matthew J. P., Zhu, Guijie, Champion, Matthew M., Medie, Felix Mba, DiGiuseppe Champion, Patricia A., Coon, Joshua J., Dovichi, Norman J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439324/
https://ncbi.nlm.nih.gov/pubmed/25893372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b00883
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