Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics

Top-down proteomics offers the potential for full protein characterization, but many challenges remain for this approach, including efficient protein separations and effective fragmentation of intact proteins. Capillary zone electrophoresis (CZE) has shown great potential for separation of intact pr...

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Publicado en:Anal Chem
Main Authors: Zhao, Yimeng, Riley, Nicholas M., Sun, Liangliang, Hebert, Alexander S., Yan, Xiaojing, Westphall, Michael S., Rush, Matthew J. P., Zhu, Guijie, Champion, Matthew M., Medie, Felix Mba, DiGiuseppe Champion, Patricia A., Coon, Joshua J., Dovichi, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439324/
https://ncbi.nlm.nih.gov/pubmed/25893372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b00883
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