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Probe dependence of allosteric enhancers on the binding affinity of adenosine A(1)‐receptor agonists at rat and human A(1)‐receptors measured using NanoBRET
BACKGROUND AND PURPOSE: Adenosine is a local mediator that regulates a number of physiological and pathological processes via activation of adenosine A(1)‐receptors. The activity of adenosine can be regulated at the level of its target receptor via drugs that bind to an allosteric site on the A(1)‐r...
Kaydedildi:
| Yayımlandı: | Br J Pharmacol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433648/ https://ncbi.nlm.nih.gov/pubmed/30644086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14575 |
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